EXTENDED SPECTRUM β-LACTAMASES (ESBL) – AN EMERGING THREAT TO CLINICAL THERAPEUTICS
نویسندگان
چکیده
منابع مشابه
Clinical significance of extended - spectrum β - lactamases
www.expert-reviews.com ISSN 1478-7210 © 2008 Expert Reviews Ltd 10.1586/14787210.6.5.671 The potential options available for treating serious infections caused by enterobacteria include penicillins (with or without β-lactamase inhibitors), cephalosporins, aztreonam, carbapenems, fluoroquinolones and, in certain situations only, aminoglycosides and colistin. Recently, tigecycline has been added ...
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ABSTRACT Background and Objectives: Pseudomonas aeruginosa is an opportunistic pathogen resistant to various antibiotics. The aim of the present study was to study resistant patterns in clinical isolates of P. aeruginosa, classify them into pandrug resistance (PDR), extensive drug resistance (XDR) and multidrug resistance (MDR)...
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Acquired resistance is through the production of AmpC Beta Lactamases (AmpC), Extended Spectrum Beta Lactamases (ESBL) and Metallo Beta-Lactamases Enzymes (MBL). Resistance to β-lactam antibiotics is associated with production of ESBL which can hydrolyze oxyimino β-lactams such as cefotaxime, ceftriaxone, ceftazidime and monobactams, however, without any effect on cephamycins, carbapenems and r...
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The current global spread of multi-resistant Gram-negatives, particularly extended spectrum β-lactamases expressing bacteria, increases the likelihood of inappropriate empiric treatment of critically ill patients with subsequently increased mortality. From a clinical perspective, fast detection of resistant pathogens would allow a pre-emptive correction of an initially inappropriate treatment. ...
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s of the International Congress of Chemotherapy, Birmingham, England, 1999). In 1989 an outbreak of multiresistant Salmonella enterica serovar Typhimurium infections occurred in 12 of 14 Argentinian provinces. From these isolates a new non-SHV, non-TEM ESBL named CTX-M-2 was identified (26, 28, 29, 333). Organisms with CTX-M-2 have spread throughout many parts of South America (333). Other CTX-...
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ژورنال
عنوان ژورنال: Indian Journal of Medical Microbiology
سال: 2004
ISSN: 0255-0857
DOI: 10.1016/s0255-0857(21)02884-x